Evidence-based Medicine Support Hardcore Academic Influence

Evidence-based Medicine:Clinical research
Clinical research and effect observation have been completed in the dermatology departments of 63 grade 3 level A hospitals.Products are endorsed by evidence-based medicine, which is the concrete evidence for the products' safety and efficacy obtained from large-scale multi-center clinical research.Botanee is actively promoting the development of China's cosmeceutical industry.

Academic Influence-Reference Book 3.0
Botanee, in collaboration with top dermatologists worldwide, has released the clinical application highlights of Winona, a cosmeceutical brand. The brand perfectly merges academic research with clinical application, playing a guiding role in the development of the dermatology and cosmeceutical industries in China.286 articles on basic research and clinical validation have been published.16 national expert guidelines and consensus have been accomplished.

A Front-line Leader:World Congress of Dermatology (WCD)
During the 23rd World Congress of Dermatology in Vancouver, Canada in June 2015, Botanee Group was the only Chinese company invited to the exhibition.In June 2019, Botanee was invited to the 24th World Congress of Dermatology in Milan, Italy. Winona, as the representative of Chinese cosmeceuticals, shone on the stage of WCD.Botanee has published the concept of precision care for sensitive skin and the findings from worldwide effect observation, garnering the attention and recognition of global dermatological authorities.In July 2023, Botanee participated in the 25th World Congress of Dermatology in Singapore, which was its third appearance at the Olympics of the Dermatology. The Botanee International Skin Health Summit was held simultaneously.Botanee presented its four core brands on such an occasion for the first time, demonstrating the new journey toward creating China's skin health ecosystem in the era of precision skincare.
Consolidate the Foundation of R&D and Innovation Enhance the Brand Image of the Group
▋ Abundant Reserves of High-barrier Products
318 ordinary cosmetics have been registered.
29 special cosmetic registration certificates have been obtained.
18 Class II medical device registration certificates have been obtained.
▋ Outstanding Achievements Made Through Collaboration Among Companies, Universities, Research Institutes, and Hospitals
Clinical research in dermatology and effect observation have been completed in 63 hospitals.
Botanee has participated in the formulation of 55 association standards for cosmeceuticals in China.
365 papers about R&D results have been included in SCI and core journals.
16 national expert guidelines and consensus have been finalized.
Global Layout 2.0: Overseas Business Expansion and Global R&D Layout
Botanee Research Institute (Shanghai)
Functional Cosmetics R&D Center, Innovative Materials R&D Centerand Medical Device R&D Department
Yunke Laboratory (Kunming)
Skin Health Research Institute, Characteristic Plant Screening Platformand Functional Food R&D Center
France Research Center (Paris)
World-leading in vitro assessment method for efficacy and safety evaluation
Japan Innovation R&D Center (Tokyo)
Focus on the innovation and R&D of sun Protection, color foundation for sensitive skinand preparation technology
Switzerland Research Center (Geneva)under preparation
Scientific research institutions for cosmetic medicine, regenerative medicine and anti-aging
Botanee Research Institute

Botanee Research Institute is located in Qingpu District, Shanghai, with a total area of more than 5,000 m2. The R&D team covers many disciplines such as pharmaceutical preparations, pharmaceutical analysis, pharmacy, high polymer chemistry, biology and fine chemical engineering.Botanee Research Institute independently develops plant actives with clear efficacy and controllable quality by combining the pathogenesis mechanism of problematic skin and exploring characteristic plant resources in Yunnan. At the same time, it screens raw materials worldwide, designs formulations and processes using pharmaceutics theory, passes rigorous in vivo/in vitro safety/efficacy screening, human sensory and human efficacy evaluation, organizes product filing and obtains relevant approval after confirming preparation parameters for pilot production. After the products finally pass clinical validation, Botanee Research Institute organizes production and sales. This scientific and rigorous R&D process has laid a quality foundation for the industry-leading innovative R&D of our products.
Yunnan Characteristic Plant Extraction Laboratory

Yunnan Characteristic Plant Extraction Laboratory has established a systematic screening and evaluation system for active substances derived from Yunnan characteristic plants, and realized commercial production of those plants.
Guided by national strategies and major scientific and technological innovation needs of Yunnan, the laboratory focuses on Yunnan characteristic plant industry, gathers superior resources inside and outside Yunnan, aims at the international frontier, drives sustainable and high-end development of the industry through R&D of cutting-edge and forward-looking technologies, establishes a new mechanism for rational distribution of revenue from transformation of scientific research achievements, and builds a whole chain of high-tech innovative business: "basic theoretical research-application and development-key generic technology development for industrialization-industrial incubation-marketing".
In November 2022, Yunnan Characteristic Plant Extraction Laboratory became the 37th "Co-certification Laboratory on National Reference Materials for Natural Products" in China granted by the Specialistic Group on Natural Product of National Technical Committee on Reference Materials.